Author
University of OttawaORCID 0000-0003-4114-0985Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
4 papers
Recent·Most cited
Margarita Lui, Olivia Makinson, Meghan L Walsh…·Ian A. J. Lorimer
This paper studies immune responses in a mouse model of glioblastoma, finding that large tumors induce immune responses at border sites but also generate immunosuppressive necroses that limit therapeutic benefit.
Leonard Angka, Gayashan Tennakoon, David P. Cook…·Rebecca C. Auer
The paper identifies PI3K-gamma signaling as a key pathway in surgery-induced MDSCs that suppresses NK cells and promotes metastases, showing that targeting this pathway can reduce postoperative metastases.
Jood Madani, Jiafeng Li, Ma. Enrica Angela Ching…·Angela M. Crawley
This study shows that chronic liver fibrosis leads to systemic CD8+ T cell hyperfunction, impairing tumor control and immune response.
Valeria Vasilyeva, Olivia Makinson, Cynthia S. Y. Chan…·Marie Marotel
This study identifies LAG3 as a marker of dysfunctional NK cells that are activated but hyporesponsive in various inflammatory conditions.