Philip M. Hansbro

This study identifies TNF and IL-1β as key drivers of endothelial dysfunction and coagulopathy in acute SARS-CoV-2 infection using in vitro and in vivo models.

This study develops a chimeric spike antigen vaccine (CoVEXS5) that induces broad immunity against multiple SARS-CoV-2 variants and other sarbecoviruses in animal models.

This study shows that iron metabolism influences influenza A virus infection and disease by altering gene expression, increasing viral titer, and worsening inflammation, with TFR1 inhibition offering protection.

This paper develops a rapid antigen test using upconversion nanoparticles for COVID-19, achieving high sensitivity and specificity in clinical trials.

This study investigates the interaction between osteoprotegerin and fibulin-1 in lung fibrosis, finding they form a complex with fibulin-1 bridging OPG and LTBP1, influencing extracellular matrix deposition.

This study shows that fecal microbial transfer and complex carbohydrates can reduce COPD symptoms in mice and humans, linking gut microbiota to disease progression.