Róbert Langer

This study uses AI to rapidly develop thermostable mRNA vaccines that maintain bioactivity at high temperatures and can be delivered via microneedle patches.

The paper analyzes CGM data to understand hypoglycemia kinetics in T1D patients, leading to the development of new glucagon delivery systems for improved therapy.

The paper introduces ExRPath and 15ExMPath techniques to expand human brain tissue for nanostructure analysis, revealing amyloid nanoclusters associated with SARS-CoV-2 in COVID-19 patients.

The paper constructs a 3D human brain model integrating multiple cell types to study Alzheimer's Disease mechanisms linked to APOE4.

This study identifies an inflammation-driven gene module in brain endothelial cells that compromises BBB integrity in Alzheimer's disease and shows that an NF-κB inhibitor can reverse these effects.

The paper develops a 3D Brain-Chip system using human iPSC-derived cells to model the BBB and study APOE4's role in Alzheimer's disease.

This paper designs prime editors with repositioned DNA breaks to significantly reduce indel errors while maintaining editing efficiency.

The paper develops a bioresorbable implant system for long-term contraception that improves drug delivery efficiency and reduces the need for surgical intervention.

This paper develops e-GLUE, an electroadhesive hydrogel interface that enables prolonged mucosal retention and demonstrates its utility in GI theranostics.

This study develops an engineered whole-lung tissue model to study tissue organization and alveolar barrier function, showing improved barrier function with alveolar macrophages.

This study develops thermo-responsive hydrogels that target inflamed colon mucosa for IBD treatment by exploiting charge-mediated interactions and thermo-responsiveness.