Mark W. Majesky

This study shows that KLF4 in smooth muscle cell-derived progenitor cells drives AngII-induced cardiac inflammation and fibrosis by promoting a profibrotic phenotype.

This study compares ECM proteomic changes during ear punch regeneration in Acomys cahirinus and Mus musculus, identifying differences in ECM proteins, crosslinking enzymes, and CD206 expression.

This study shows that Klf4-dependent transitions in adventitial progenitor cells affect plaque stability in atherosclerosis by altering fibroblast, SMC, and macrophage phenotypes.

The paper presents an improved chromosome-scale genome assembly for the African spiny mouse using long Nanopore reads and validates it with RNA-seq data.

This study shows that pericyte loss in aged brains leads to capillary dilation, flow heterogeneity, and structural disruption, highlighting pericyte remodeling as a therapeutic target.

This study shows that Pbx factors are essential for embryonic fast-twitch muscle differentiation in both zebrafish and mice, with conserved gene regulation mechanisms.

This study shows African Spiny mice can repair kidney injury without fibrosis, unlike mice, suggesting evolutionary adaptations for organ regeneration.