Chrysostomi Gialeli

Endothelial Twist1 drives partial and advanced endothelial-to-mesenchymal transition via PELP1 and AEBP1-COL4A1 signaling, increasing collagen and ACTA2+ cells to stabilize atherosclerotic plaques in male mice and human carotid arteries.

This paper identifies FOL-026, an osteopontin-derived peptide that binds neuropilin-1 and activates vascular cells, mimicking VEGF effects and showing potential for vascular repair.

The paper investigates the role of CSMD1 in opposing the complement cascade in neural tissues and links its dysfunction to schizophrenia risk.