Author

Leah F. Cabo

University of PittsburghORCID 0000-0003-4328-9900Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Carolyn B. CoyneiD· 2 shared Jon P. BoyleiD· 2 shared Liheng YangiD· 2 shared Rafaela José da SilvaiD· 2 shared Christina MegliiD· 1 shared Jada L. GeorgeiD· 1 shared Laty A. CahooniD· 1 shared Mingze GaoiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersDevelopmental Biology

Carolyn B. CoyneORCID

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2 papers

Recent·Most cited

Developmental BiologyCell ReportsPeer-reviewedFeb 1, 2026

Toxoplasma gondii infection misdirects placental trophoblast lineage specification

Leah F. Cabo, Liheng Yang, Mingze Gao…·Jon P. Boyle

This study shows that Toxoplasma gondii infection redirects placental trophoblast lineage specification, promoting infection-permissive cells over infection-resistant ones.

DOI 10.1016/j.celrep.2025.116825

mousebulk RNA-seq

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MicrobiologymSpherePeer-reviewedMay 21, 2024

Human trophoblast stem cells can be used to model placental susceptibility to Toxoplasma gondii and highlight the critical importance of the trophoblast cell surface in pathogen resistance

Rafaela José da Silva, Leah F. Cabo, Jada L. George…·Jon P. Boyle

This study uses human trophoblast stem cells to model placental resistance to Toxoplasma gondii and Listeria monocytogenes, showing that syncytiotrophoblasts are more resistant than cytotrophoblasts.

8 citations

humanbulk RNA-seq

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