Seul K Jung

The paper develops a method to quantify hematopoietic precursors in mice, showing their contribution to both normal and perturbed hematopoiesis, and applies it to a Fanconi Anemia model.

This study shows that healthy hematopoietic stem and progenitor cells (HSPCs) adopt inflammatory gene expression programs in the AML niche, driven by AML-derived extracellular vesicles.