Empar Baltasar Pérez

This paper creates a cross-species single-cell atlas of Macaca fascicularis using human reference labels to improve target qualification and toxicity interpretation in preclinical research.

The paper identifies genes critical for the replication stress response in human cells, revealing both known and novel factors that protect against replication stress-induced toxicity.

This study shows that healthy hematopoietic stem and progenitor cells (HSPCs) adopt inflammatory gene expression programs in the AML niche, driven by AML-derived extracellular vesicles.