Author

Alexus Locke

Johns Hopkins UniversityORCID 0000-0003-4475-101XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1 Assay:proteomics· 1 Organism:zebrafish· 1

Frequent Co-Authors

Alexandra SneideriD· 1 shared Arrate Muñoz‐BarrutiaiD· 1 shared Bartholomew StarichiD· 1 shared Carolyn MarariD· 1 shared Daniel M. LewisiD· 1 shared Denis WirtziD· 1 shared Estibaliz Gómez‐de‐MariscaliD· 1 shared Gabriella C. RussoiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alexandra SneiderORCID

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1 paper

Recent·Most cited

Cancer BiologyCancer Research CommunicationsPeer-reviewedApr 17, 2024

Small extracellular vesicles promote stiffness-mediated metastasis

Alexandra Sneider, Ying Liu, Bartholomew Starich…·Denis Wirtz

The paper shows that breast cancer cell-derived small extracellular vesicles (EVs) become more adhesive and metastatic when produced in stiff matrices, promoting cancer spread through enhanced chemotaxis and fibroblast reprogramming.

30 citations

mousezebrafish

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