Donata Hoffmann

This study compares the susceptibility of different species to bat-borne H9N2 influenza virus, finding that Eidolon helvum is highly susceptible and transmits efficiently, while pigs and quails are not.

This paper develops a multi-species luciferase-based double antigen ELISA for detecting H5 clade 2.3.4.4b-specific antibodies in various species, showing high sensitivity and specificity.

This study evaluates a human DPP4 transgenic hamster model for MERS-CoV infection and transmission, showing efficient viral replication and similar clinical outcomes with two MERS-CoV strains.

The paper assesses pre-existing humoral immunity against H5N1 clade 2.3.4.4b in unexposed individuals and finds low but distinct cross-neutralizing titers.

This study investigates H5N1 clade 2.3.4.4b virus infection in calves and lactating cows, finding that mammary gland infection causes severe mastitis and reduced milk production, with transmission likely via milk rather than respiratory routes.

This paper shows that MPXV infects human PBMCs in a type I interferon-sensitive manner, with monocytes, cycling NK cells, and regulatory CD4+ T-cells as susceptible cell types.

The paper identifies a diverse virome in European white-toothed shrews, including novel viral species related to WHO priority pathogens, and highlights their potential role in zoonotic spillover.

This study develops a single-cycle SARS-CoV-2 vaccine that provides full protection and sterilizing immunity in hamsters against autologous challenge.