ImmunologyNature CommunicationsPeer-reviewed
The Identification of IL-4 as a Regulator of Chimeric Antigen Receptor T Cell Exhaustion
Carli M. Stewart, Elizabeth L. Siegler, Reona Leo Sakemura…·Saad S. Kenderian
This study identifies IL-4 as a regulator of CART cell exhaustion and shows that IL-4 neutralization improves antitumor efficacy.