Arvind H. Patel

This study shows that the SARS-CoV-2 Spike H655Y mutation changes protease preference but does not determine cellular tropism, with RBD interactions being more critical for upper airway adaptation.

This study shows SARS-CoV-2 E protein induces LC3 lipidation through the V-ATPase-ATG16L1 axis, which supports viral replication rather than inhibiting it.

This study shows that PROS1 released by lung basal cells during SARS-CoV-2 infection reduces inflammation, promotes epithelial repair, and enhances antigen presentation.

The paper assesses the virulence of the SARS-CoV-2 BA.2.86 variant in hamsters and finds it is attenuated compared to BA.2.75.

The paper systematically analyzes proteomic and genomic data of SARS-CoV-2 variants to identify how mutations affect viral gene expression, host interactions, and immune evasion.

This paper develops ZIKV vaccines using virus-like particles with covalently dimerized envelope protein, showing enhanced neutralization and protection against lethal ZIKV challenge in mice.

The paper examines the impact of IFN-lambda4 on HCV diversity using host and viral genetic data from 485 patients, finding that IFN-lambda4 variants influence viral amino acid diversity and load.