T.M. Gloster

The paper catalogs and analyzes CAZyme complements in Pectobacterium and Dickeya genomes, finding coevolution of CAZymes linked to host adaptation and tissue preference.

This study describes the structure and mechanism of Crn4, a ring nuclease that degrades cyclic oligoadenylates and modulates type III CRISPR immunity.

The paper shows that a viral SAVED domain, AcrIII-2, degrades the CRISPR second messenger cA4, inhibiting its effectors.

This study investigates the structure and function of a SAM-AMP lyase from Clostridium botulinum, showing its ability to substitute for a phosphodiesterase in providing anti-phage defence.

This study identifies Csx23 as a CRISPR effector that uses cyclic nucleotide binding to mediate antiphage defence in Vibrio cholerae.

cazy_webscraper compiles and integrates CAZyme data from CAZy and other sources, enabling large-scale bioinformatic analysis and candidate screening for biotechnological applications.