James W. Round

This study compares multimerization domains in mRNA LNP vaccines, finding that IMX313 enhances antibody responses more than other domains.

The paper uses Tope-seq to identify cross-reactive epitopes in an engineered T-cell receptor that caused off-target toxicity, highlighting the need for comprehensive screening.

This paper introduces a synthetic cytotoxic T cell platform for rapidly prototyping TCR function, demonstrating successful antigen-specific responses and preservation of antigen-presenting cells.