Rick M. Maizels

This paper shows that vaccinating against helminth IL-33-modulators can protect against infection by reversing immunosuppression and enhancing Th2 immunity.

The paper shows tuft cells release acetylcholine to directly target helminth parasites in the gut, enhancing type 2 immunity.

This study uses spatial transcriptomics to analyze gene expression changes in the small intestine of H. polygyrus-infected mice, identifying altered signaling pathways and cell interactions during infection.

The paper identifies three HpARI family members in H. polygyrus bakeri, showing they have distinct effects on IL-33-dependent Type 2 immune responses.

This paper compares genomes of 81 nematode and platyhelminth species to identify gene families related to parasitism and prioritize new drug targets.