Author
University of PittsburghORCID 0000-0003-4789-3873Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Andrew W. Simonson, Michael C. Chao, Luke E Hood…·JoAnne L. Flynn
The study shows that prior Mtb infection protects against reinfection with a genetically distinct strain in macaques, suggesting broad vaccine efficacy across Mtb lineages.
Andrew W. Simonson, Joseph John Zeppa, Allison N. Bucşan…·JoAnne L. Flynn
The paper shows that CD4 T cells and innate CD8+ lymphocytes are essential for IV BCG-induced protection against tuberculosis in macaques.
Alexander A. Smith, Hong-Wei Su, Joshua Wallach…·JoAnne L. Flynn
This study develops a 'suicide' BCG strain that is safely eliminated in immunocompromised hosts but induces stronger immune responses and better protection against Mtb in macaques.