Jim P. Haseloff

This study investigates the functional diversification of ERF transcription factors across land plants using liverwort and Arabidopsis, revealing conserved and lineage-specific roles in development and stress responses.

This study engineers auronidin production in Marchantia polymorpha to create sustainable textile pigments, demonstrating their feasibility for dyeing cotton yarn.

This paper identifies a biosynthetic gene cluster in liverwort Marchantia polymorpha that produces monoterpenes using neryl diphosphate as a substrate, revealing new insights into monoterpene biosynthesis in non-seed plants.

This study reveals how auxin transport and ARF signaling regulate stem cell maintenance and re-establishment in the liverwort Marchantia polymorpha.

This paper demonstrates the use of Marchantia polymorpha for producing functional nanobodies with high yield, comparable to Nicotiana benthamiana, offering a scalable and safe plant-based production platform.

The paper identifies ancestral MBW transcriptional complexes in liverworts, showing their role in flavonoid pathway regulation and oil body maturation, and suggests a pattern of evolutionary duplication and co-option in land plants.

This study identifies GEMMIFER (MpGMFR) as a key regulator of asexual reproduction in Marchantia polymorpha by showing its necessity and sufficiency for initiating gemma formation.

This study identifies a minimal cell-cycle control system in the liverwort Marchantia polymorpha, revealing conserved mechanisms and ancestral states of cell-cycle regulation in plants.

The paper identifies ABCG1 as critical for sesquiterpene retention in Marchantia polymorpha oil bodies through overexpression and CRISPR disruption experiments.

This paper introduces a tRNA-gRNA multiplexing system for CRISPR genome editing in Marchantia polymorpha, improving efficiency and scalability of genome modifications.

This study identifies conserved chromatin states in Arabidopsis thaliana and Marchantia polymorpha, showing their association with transcription factor binding and function across land plant evolution.

This study identifies an arsenic-sensing domain in MpACR3 that regulates its trafficking and function, revealing a plant-specific adaptation to arsenic toxicity.

This paper presents a semi-automated protocol for Agrobacterium-mediated plant transformation in Marchantia polymorpha, improving efficiency and reducing costs for high-throughput experiments.

The paper identifies MYB-related transcription factors as regulators of chloroplast biogenesis in liverworts and Arabidopsis, showing they work with GLK factors to control chloroplast development.

The paper shows that MpDCL1a is essential for miRNA biogenesis and regulates auxin synthesis, influencing cell identity and body development in the last common ancestor of land plants.

The paper introduces the OpenPlant toolkit for bioengineering in Marchantia polymorpha, enabling efficient plant transformation and gene expression studies without specialized facilities.

The paper introduces Loop assembly, a method for efficiently and parallelly constructing large DNA circuits using two Type IIS restriction endonucleases and standardised parts.

This paper demonstrates a droplet-based microfluidic system for analyzing plant protoplasts, enabling high-throughput phenotyping and gene expression analysis.

This paper develops a synthetic genetic system for programmed hierarchical patterning of bacterial gene expression domains using population-based AND logic.