Author

Adam J. Sugarman

Albert Einstein College of MedicineORCID 0000-0003-4946-5979Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Aidin Shabro· 1 shared Antonio Di CristofanoiD· 1 shared Luong Do HuynhiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperCancer Biology

Aidin Shabro

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1 paper

Recent·Most cited

Cancer BiologyCancer LettersPeer-reviewedApr 30, 2023

Anaplastic Thyroid Cancer Cells Upregulate Mitochondrial One-Carbon Metabolism To Meet Purine Demand, Eliciting A Critical Targetable Vulnerability

Adam J. Sugarman, Luong Do Huynh, Aidin Shabro, Antonio Di Cristofano

This study identifies upregulated mitochondrial one-carbon metabolism in anaplastic thyroid cancer as a targetable vulnerability, showing that inhibiting SHMT2 reduces proliferation and tumor growth.

15 citations

mousehuman

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