Gabriele Allies

SIMO integrates spatial metabolomics, lipidomics, and proteomics from a single tissue section to enable comprehensive multi-omics analysis across spatial regions.

This study identifies polyamines as key regulators of epithelial regeneration in aged intestines, showing they enhance protein homeostasis and restore regenerative capacity through dietary manipulation.

This study shows autophagy is essential for maintaining HEV function and expansion during inflammation, ensuring proper PNAd production and lymphocyte homing.

This study shows that constitutive IκBζ expression in melanoma promotes tumor growth and immunotherapy resistance by suppressing cytokine production and immune cell recruitment.

This study shows that pathogenic mtDNA mutations in melanoma cells reduce metastasis by limiting circulation entry, despite promoting tumor growth.