Author

Lars Borgards

Essen University HospitalORCID 0009-0000-2362-4674Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:differential expression· 2 Approach:experimental assay· 1 Approach:machine learning (classical)· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

Bente SiebelsiD· 3 shared Christoph KrispiD· 3 shared Daniel Robert EngeliD· 3 shared Devon SiemesiD· 3 shared Florian WagenlehneriD· 3 shared Hannah VoßiD· 3 shared Hartmut SchlüteriD· 3 shared Jan Hinrich BraeseniD· 3 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersImmunology

Bente SiebelsORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

ImmunologybioRxivPreprintApr 14, 2026

Integrated kidney and urine proteomics define encrypted antimicrobial peptides as effectors of host defence in human pyelonephritis

Lars Borgards, Hannah Voß, Stephanie Tautges…·Olga Shevchuk

The paper integrates kidney and urine proteomics with peptidomics and machine learning to identify encrypted antimicrobial peptides as functional effectors in human pyelonephritis.

DOI 10.64898/2026.04.10.717476

humanproteomics

𝕏 PostBluesky

ImmunologybioRxivPreprintApr 13, 2026

Lactate-dependent metabolic rewiring is associated with CD163+ macrophage polarization in human pyelonephritis

Lars Borgards, Hannah Voß, Stephanie Tautges…·Daniel Robert Engel

This study identifies lactate as a metabolic driver of CD163+ macrophage polarization in human pyelonephritis, linking lactate metabolism to immune dysfunction.

DOI 10.64898/2026.04.09.717269

humanproteomics

𝕏 PostBluesky

ImmunologybioRxivPreprintSep 14, 2023

Proteomic adaptations in the kidney reveal orchestration of local and secreted antimicrobial peptides in human pyelonephritis

Lars Borgards, Bente Siebels, Hannah Voß…·Olga Shevchuk

This study identifies proteomic adaptations in human pyelonephritis, revealing elevated antimicrobial peptides and their potential protective role against systemic inflammation.

2 citations

humanproteomics

𝕏 PostBluesky