Author

Bashir A. Ali

University of California, Santa BarbaraORCID 0009-0000-4604-3012Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:yeast· 2 Approach:biophysical modeling· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Brooke M. GardneriD· 2 shared Chris D. RichardsoniD· 2 shared Andreas MartiniD· 1 shared Connor J. SheedyiD· 1 shared Dominic T. CastanzoiD· 1 shared Eric Z. PangiD· 1 shared Gabriel C. LanderiD· 1 shared Julia Miyamoto· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersBiochemistry

Brooke M. GardnerORCID

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2 papers

Recent·Most cited

BiochemistryJournal of Biological ChemistryPeer-reviewedMar 31, 2025

PEX1G843D remains functional in peroxisome biogenesis but is rapidly degraded by the proteasome

Connor J. Sheedy, Soham P. Chowdhury, Bashir A. Ali…·Brooke M. Gardner

This study shows that the PEX1G843D mutation impairs PEX1/PEX6 assembly and leads to proteasomal degradation, but overexpression can restore peroxisome function.

4 citations

yeasthuman

𝕏 PostBluesky

BiochemistryJournal of Biological ChemistryPeer-reviewedNov 29, 2023

The Pex6 N1 domain is required for Pex15 binding and proper assembly with Pex1

Bashir A. Ali, Ryan M. Judy, Saikat Chowdhury…·Brooke M. Gardner

This study identifies the Pex6 N1 domain's role in binding Pex15 and stabilizing the Pex1/Pex6 heterohexamer, essential for peroxisome function.

6 citations

yeaststructural biology

𝕏 PostBluesky