Author
University of California, Santa BarbaraORCID 0000-0002-9161-7182Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Soham P. Chowdhury, Sambhav Jain, Milagros Esmerode…·Brooke M. Gardner
This study shows that PEX1 deficiencies disrupt HIF1α proteostasis via autophagy, leading to increased HIF1 levels and impaired recovery under hypoxia-reoxygenation.
Wyatt D. Miller, Andrew Manion, Abhinava K. Mishra…·Meghan A. Morrissey
This study shows CD47 inhibits Rac-mediated phagocytosis by preventing Vav1 phosphorylation, shifting the mechanism from Rac-based reaching to Rho-based sinking.
Connor J. Sheedy, Soham P. Chowdhury, Bashir A. Ali…·Brooke M. Gardner
This study shows that the PEX1G843D mutation impairs PEX1/PEX6 assembly and leads to proteasomal degradation, but overexpression can restore peroxisome function.
Jonathan T. Vu, Katherine U. Tavasoli, Connor J. Sheedy…·Brooke M. Gardner
The paper identifies RNF146 and tankyrase as regulators of peroxisome function and links them to Wnt signaling through their role in PARsylation and beta-catenin degradation.