ImmunologybioRxivPreprint
A new humanized TCR transgenic mouse model to study citrullinated tenascin C reactive T cells relevant to rheumatoid arthritis
Marlene Schülein, M. Gomes Afonso, Merel Sijbranda…·Bruno Raposo
DOI 10.64898/2026.02.12.705563
Author
St. Jude Children's Research HospitalORCID 0009-0000-5671-537XUnclaimed ORCID profile · follow to get notified of new preprints
2 papers
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Marlene Schülein, M. Gomes Afonso, Merel Sijbranda…·Bruno Raposo
Diego Velasquez Pulgarin, Nathalie Pelo, Lin Ferrandiz…·Alexander Espinosa
This paper introduces BLU-VIPR, an optogenetic CRISPR tool that enables precise spatiotemporal gene editing in T lymphocytes in vivo by regulating gRNA production with blue light.