Author

Sajina Dhungel

University of KentuckyORCID 0009-0000-6453-5950Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell type annotation· 2 Approach:deep learning· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Chintan K. KikaniiD· 4 shared Rajaian Pushpabai RajeshiD· 3 shared Michael J. XiaoiD· 2 shared Aanya Parasramka· 1 shared Aarush Kikani· 1 shared Brian Kelly· 1 shared Chia-Hua WuiD· 1 shared Dean R TantiniD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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4 shared papersBiochemistry

Chintan K. KikaniORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Cell BiologybioRxivPreprintMar 27, 2026

A Deep-Learning Atlas of XPO1-Mediated Nuclear Export at Proteome Scale

Sajina Dhungel, Sihara de Zoysa, DeAnna Burns…·Chintan K. Kikani

The paper uses deep learning to create an atlas of XPO1-mediated nuclear export, identifying thousands of new NESs and revealing structural patterns and regulatory mechanisms.

DOI 10.64898/2026.03.25.713363

humanproteomics

𝕏 PostBluesky

BiochemistrybioRxivPreprintOct 2, 2025

Glutamine-Dependent Slc25a39-Nrf2 Axis Couples Mitochondrial Dynamics with Metabolic Reprogramming to Establish Myogenic Commitment

Brian Kelly, Chia-Hua Wu, Kaan Ihsan Eskut…·Chintan K. Kikani

DOI 10.1101/2025.10.02.680066

mousebulk RNA-seq

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BiochemistryProceedings of the National Academy of SciencesPeer-reviewedMar 19, 2025

Nutrient Signaling-Dependent Quaternary Structure Remodeling Drives the Catalytic Activation of metazoan PASK

Sajina Dhungel, Michael J. Xiao, Rajaian Pushpabai Rajesh, Chintan K. Kikani

This study identifies a nutrient-responsive quaternary structure remodeling in metazoan PASK through structural and evolutionary analysis, linking nutrient sensing to catalytic activation.

3 citations

humanmouse

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BiochemistryJournal of Molecular BiologyPeer-reviewedSep 6, 2023

Signal-regulated unmasking of the nuclear localization motif in the PAS domain regulates the nuclear translocation of PASK.

Michael J. Xiao, Sajina Dhungel, Roksana Azad…·Chintan K. Kikani

This study identifies a mechanism by which PASK's nuclear translocation is regulated by the interaction between its PAS-A domain and a PIM motif, which is modulated by metabolic signals.

2 citations

humanproteomics

𝕏 PostBluesky