Author

Junsen Lin

Peking UniversityORCID 0009-0000-7379-4161Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Blake D. JardiniD· 2 shared Congting GuoiD· 2 shared Luzi YangiD· 2 shared Mingming Zhao· 2 shared William T. PuiD· 2 shared Yuxuan GuoiD· 2 shared Canzhao LiuiD· 1 shared Chenyang WuiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersCell Biology

Blake D. JardinORCID

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2 papers

Recent·Most cited

Cell BiologyJACC Basic to Translational SciencePeer-reviewedAug 23, 2024

Non-cell autonomous cardiomyocyte regulation complicates gene supplementation therapy for LMNA cardiomyopathy

Yueshen Sun, Congting Guo, Zhan Chen…·Yuxuan Guo

This study shows that gene supplementation for LMNA cardiomyopathy is ineffective when targeting cardiomyocytes alone, as non-cell autonomous effects dominate, suggesting alternative therapeutic targets.

7 citations

mouseexperimental assay

𝕏 PostBluesky

Molecular BiologybioRxivPreprintDec 6, 2023

In vivo proximity proteomics uncovers palmdelphin (PALMD) as a Z-line-associated mitigator of isoproterenol-induced cardiac injury

Congting Guo, Blake D. Jardin, Junsen Lin…·Yuxuan Guo

This study identifies PALMD as a Z-line-associated protein that mitigates cardiac injury through stabilization of NEXN using in vivo proximity proteomics.

DOI 10.1101/2023.12.06.570334

mousehuman

𝕏 PostBluesky