Author

Michael A. LaPorta

Salk Institute for Biological StudiesORCID 0009-0001-0461-5614Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Susan M. KaechiD· 2 shared Aaron P. HavasiD· 1 shared Adarsh RajeshiD· 1 shared Alexandra C. NewtoniD· 1 shared Anatoly Korotkov· 1 shared Andrei SeluanoviD· 1 shared Andrew E. M. DavisiD· 1 shared Anna-Maria GlobigiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCell Biology

Susan M. KaechORCID

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2 papers

Recent·Most cited

Cell BiologyNature CommunicationsPeer-reviewedMar 5, 2025

Linked regulation of genome integrity and senescence-associated inflammation by p53

Karl N. Miller, Brightany Li, Hannah R. Pierce-Hoffman…·Peter D. Adams

This study identifies a mitochondria-regulated p53 circuit that links genomic instability and inflammation in senescent cells, showing p53 suppresses inflammation without affecting cell cycle arrest.

49 citationstop 1%

mouseDNA methylation

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ImmunologybioRxivPreprintSep 26, 2024

Different signaling interpretations by PKC eta and theta control T cell function and exhaustion

Thomas H. Mann, Hannah M. Knox, Shixin Ma…·Susan M. Kaech

This study shows PKC theta sustains T cell function while PKC eta drives terminal exhaustion, with distinct downstream cascades and therapeutic implications for cancer immunotherapy.

1 citation

humanproteomics

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