Susana Mellado

This study identifies sex-specific miRNA profiles in urinary extracellular vesicles of alcohol use disorder patients, revealing potential biomarkers and mechanistic insights into sex differences in AUD.

This study characterizes the lipidomic profile of urine extracellular vesicles in male alcohol use disorder patients, identifying FA 22:0 as a potential biomarker linked to inflammation and metabolic dysfunction.

This study integrates miRNomic and lipidomic analysis of plasma extracellular vesicles from AUD patients and controls to identify sex-based molecular signatures and their functional implications.

This study evaluates the anti-diabetic and anti-inflammatory effects of Periploca laevigata extracts on pancreatic β cells under hyperglycaemic conditions, showing upregulation of insulin and PDX-1 and downregulation of inflammatory markers.

This study shows that chronic OEA treatment after stress reduces stress-induced alcohol consumption in mice, but not relapse-like behavior.

This study investigates the effects of MSC-EVs on neuroinflammation and behavioral impairments caused by chronic alcohol consumption in mice, finding that MSC-EVs reduce inflammation and improve cognitive and addictive-like behaviors.

This study investigates how TLR4 and sex affect lipidome changes in EVs from chronically alcohol-exposed mice, identifying lipid subclasses linked to inflammation and EV biogenesis.

This study shows that mesenchymal stem cell-derived extracellular vesicles reduce hippocampal NLRP3 inflammasome activation and inflammation in adolescent mice after binge ethanol treatment.

This study investigates how OEA affects alcohol self-administration and gene expression in specific brain regions, finding region-specific changes in dopamine and cannabinoid receptor genes and immune responses.

This study uses lipidomics to analyze plasma extracellular vesicles from AUD patients and healthy individuals, revealing sex-based differences in lipid profiles and their potential links to disease mechanisms.