Grace Nye

Cryo-EM at 2.9-3.1 Å shows bacterial OLE, ROOL and GOLLD RNAs self-assemble without protein into a dimer, an 8-chain nanocage and a 14-chain nanocage.

This paper determines the 3D structures of SL5 RNA domains from six coronaviruses, revealing conserved tertiary features with implications for protein-binding and antiviral targets.

The paper introduces RibonanzaNet, a deep learning model trained on crowdsourced RNA chemical mapping data to predict RNA structure and related properties.