Lucie A.G. van Leeuwen

The paper develops FlyPer, a Drosophila H2O2 biosensor toolkit, to measure subcellular H2O2 dynamics in vivo, revealing tissue-specific redox patterns during development and stress.

This study shows that enhancing autophagy through redox regulation extends lifespan in Drosophila by highlighting the role of a specific cysteine residue in Atg4a.