Author

Sophie G. Paradi

Washington University in St. LouisORCID 0009-0002-6991-9907Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Erica V. ElyiD· 2 shared Farshid GuilakiD· 2 shared Kelsey H. CollinsiD· 2 shared Abraham Behrmann· 1 shared Ashlyn T Kapinski· 1 shared Kristin L. LenziD· 1 shared Lauryn A. BraxtoniD· 1 shared Ruhang TangiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersPhysiology

Erica V. ElyORCID

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2 papers

Recent·Most cited

PhysiologyArthritis Research & TherapyPeer-reviewedJul 19, 2025

Chondrocyte-Specific Knockout of Piezo1 and Piezo2 Protects Against Post-Traumatic Osteoarthritis Structural Damage and Pain in Mice

Erica V. Ely, Kristin L. Lenz, Sophie G. Paradi…·Farshid Guilak

This study shows that knocking out Piezo1 and Piezo2 in chondrocytes protects against post-traumatic osteoarthritis structural damage and pain in mice.

16 citationstop 1%

mouseexperimental assay

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BioengineeringEuropean Cells and MaterialsPeer-reviewedDec 29, 2023

Designer Fat Cells: Adipogenic Differentiation of CRISPR-Cas9 Genome-Engineered Induced Pluripotent Stem Cells

Erica V. Ely, Ashlyn T Kapinski, Sophie G. Paradi…·K. H.-M. Collins

This paper develops a method to generate genetically engineered adipocytes from murine iPSCs using CRISPR-Cas9 and tests their engraftment and functional properties in vivo.

DOI 10.22203/ecm.v046a09

mousegenetic perturbation / CRISPR

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