Chaoyu Fu

The paper shows how chiral multicellular patterns arise from actin self-organisation in cells, with chiral order starting at tissue boundaries and propagating inward.

This study investigates the mechanotransduction mechanism of ADGRG1/GPR56, revealing a dual-mode activation process that does not require NTF-CTF dissociation and depends on the Stachel element.

This study introduces a new method to measure energy dissipation during cell-cell junction rupture and shows that cortical tension and shape relaxation time determine whether junctions behave ductile or brittle.

The paper demonstrates that disrupting super-silencers via EZH2 and REST inhibition reduces chromatin interactions and cancer growth.

The paper identifies 'super-silencers' formed by chromatin interactions that regulate apoptotic genes and shows that combining GSK343 and X5050 disrupts these silencers to induce antitumor effects.