Author

Alyssa N. Ho

University of North Carolina at Chapel HillORCID 0009-0003-1797-6907Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

Elaine M. GlennyiD· 2 shared Michael F. ColemaniD· 2 shared Stephen David HurstingiD· 2 shared Amanda L. KucinskasiD· 1 shared Brian P. RiesenbergiD· 1 shared C. Alex HoltiD· 1 shared Caroline Marnata· 1 shared Claire E. GatesiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

Elaine M. GlennyORCID

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2 papers

Recent·Most cited

Cancer Biologynpj Breast CancerPeer-reviewedSep 29, 2026

Obesity Impairs the Antitumor Activity of CAR-T Cells in Triple-Negative Breast Cancer

Hannah M. Malian, Caroline Marnata, Hannah M. Oh…·Michael F. Coleman

This study shows obesity impairs B7-H3.CAR-T cell antitumor activity and memory formation in TNBC by altering cytokine profiles and metabolic function.

2 citationstop 3%

mousebulk RNA-seq

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Cancer BiologybioRxivPreprintJan 20, 2024

Tirzepatide restricts obesity-related tumor growth by reversing metabolic dysregulation and rescuing CD8+ T cell function

Elaine M. Glenny, Michael F. Coleman, Genevieve T. Clutton…·Stephen David Hursting

This study shows tirzepatide reduces obesity-related tumor growth by improving metabolism and restoring CD8+ T cell function without directly targeting cancer cells.

18 citations

mouseexperimental assay

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