Marc Gabriel

This study shows that the p53Y217C mutation causes inflammation, leading to oncogenic effects in male mice and teratogenic effects in female mice, with anti-inflammatory treatment improving female survival.

The paper shows that male-specific protection against Myc-driven B-cell lymphomas is lost in mice lacking alternatively spliced p53 isoforms, identifying Ackr4 as a prognostic factor.

The paper introduces a reference-free computational method to identify novel RNAs for prostate cancer diagnosis, finding that 9 unannotated lncRNAs outperform existing biomarkers.

This paper introduces DE-kupl, a k-mer-based method to capture RNA variation without a reference, identifying novel transcripts and biological events from RNA-seq data.

The paper shows that decapping prevents RDR6-dependent production of rqc-siRNAs from endogenous mRNAs, revealing a link between RNA quality control and post-transcriptional gene silencing in plants.