Cancer BiologyNature CommunicationsPeer-reviewed
The ESCRT protein CHMP5 promotes T cell leukemia by controlling BRD4-p300-dependent transcription
Katharine Umphred-Wilson, Shashikala Ratnayake, Qianzi Tang…·Stanley Adoro
This paper identifies CHMP5 as a nuclear factor that promotes T cell leukemia by enhancing BRD4-p300-dependent transcription at enhancers and super-enhancers.