Author

Desiree Francis

University of GuelphORCID 0009-0004-9003-5043Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Organism:C. elegans· 2 Research Focus:drug response / drug discovery· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

Rebecca S. ShapiroiD· 2 shared Abdul-Rahman Adamu BukariiD· 1 shared Aleeza C. GersteiniD· 1 shared Anthony HendriksiD· 1 shared Chris Grant· 1 shared Christian R. LandryiD· 1 shared Christina A. CuomoiD· 1 shared Clara FikryiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

Rebecca S. ShapiroORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintJan 8, 2026

Pooled CRISPRi screening reveals fungal-specific vulnerabilities across environments and genetic backgrounds

Lauren F. Wensing, Philippe C Després, Desiree Francis…·Rebecca S. Shapiro

This study uses pooled CRISPRi screening in Candida albicans to identify dosage-sensitive genes across diverse environments and genetic backgrounds, highlighting potential antifungal targets.

1 citation

C. elegansgenetic perturbation / CRISPR

𝕏 PostBluesky

Microbiologynpj Antimicrobials and ResistancePeer-reviewedNov 29, 2024

A role for the putative error-prone polymerase REV1 in DNA damage and antifungal drug resistance in Candida albicans

Michelle R. Agyare-Tabbi, Deeva Uthayakumar, Desiree Francis…·Rebecca S. Shapiro

This study investigates the role of REV1, an error-prone polymerase, in DNA damage and antifungal drug resistance in Candida albicans, finding that its deletion increases mutation rates and resistance.

6 citations

C. elegansDNA methylation

𝕏 PostBluesky