Katelyn R. Ludwig

This study links metabolic and inflammatory changes to arterial stiffness in ultra-endurance runners using multi-omics analysis of plasma samples.

This study shows that methylglyoxal-induced glycation stress causes aortic stiffening through oxidative stress and cellular senescence, and a glycation-lowering compound mitigates these effects.

This study shows that doxorubicin chemotherapy induces aortic stiffening via cellular senescence and the senescence-associated secretory phenotype, which can be mitigated by senolytic therapy.

This study identifies two visual modalities of EWSR1 in the nucleoplasm, both associated with nascent RNA, and shows EWSR1 foci localize to euchromatin and phosphorylated RNA polymerase II.

The paper shows HNRNPH1 destabilizes G-quadruplexes in G-rich RNA sequences, affecting alternative splicing of an oncogenic fusion transcript in Ewing sarcomas.