Shigetada Kawabata

This study shows glycerol inhibits lactose-dependent growth in Streptococcus pyogenes without affecting transcription, while lactose induces distinct transcriptional responses.

The paper identifies genetic variations in emm89 Streptococcus pyogenes associated with invasive infections using genome-wide association studies and validates one mutation's effect on bacterial growth.

This study identifies S. pyogenes gene-expression changes in a mouse necrotizing fasciitis model, revealing upregulation of virulence factors and downregulation of oxidative-stress response genes.