Masaya Yamaguchi

This study uses real-time near-infrared imaging to distinguish nasopharyngeal colonization from aspiration of Streptococcus pneumoniae and shows aspiration triggers severe disease.

This study shows retinoid signaling specifies frontonasal identity and represses maxillary identity in cranial neural crest cells during facial development in mice.

The paper identifies genetic variations in emm89 Streptococcus pyogenes associated with invasive infections using genome-wide association studies and validates one mutation's effect on bacterial growth.

This study identifies S. pyogenes gene-expression changes in a mouse necrotizing fasciitis model, revealing upregulation of virulence factors and downregulation of oxidative-stress response genes.