Author

Giuseppe Giuliani

Nationwide Children's HospitalORCID 0009-0005-5832-7430Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Organism:human· 2 Research Focus:spatial domain detection· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1

Frequent Co-Authors

Jayajit DasiD· 3 shared Ciriyam JayaprakashiD· 2 shared William C. StewartiD· 2 shared Zihai LiiD· 2 shared Darren WethingtoniD· 1 shared Dhruv ChavaniD· 1 shared Joseph Chai-Yuen SuniD· 1 shared Lewis L. LanieriD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersImmunology

Jayajit DasORCID

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3 papers

Recent·Most cited

Cancer BiologyComputational and Structural Biotechnology JournalPeer-reviewedJan 1, 2025

Immune and non-immune cell fencing of tumor cells is a widespread and functionally relevant spatial pattern in solid cancers

Giuseppe Giuliani, Dhruv Chavan, Rushil Gaddam…·Jayajit Das

The paper examines spatial fencing patterns of tumor cells by immune and non-immune cells in solid cancers and links these patterns to cancer progression and treatment response.

2 citations

humanbulk RNA-seq

𝕏 PostBluesky

ImmunologyPNAS NexusPeer-reviewedNov 26, 2024

Spatial organization and stochastic fluctuations of immune cells impact clinical responsiveness to immune checkpoint inhibitors in patients with melanoma

Giuseppe Giuliani, William Stewart, Zihai Li…·Jayajit Das

The paper develops a spatially resolved model to show how immune cell organization and dynamics influence response to immune checkpoint inhibitors in melanoma patients.

6 citations

humanspatial transcriptomics

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ImmunologybioRxivSep 7, 2023

Clonal stochasticity in early NK cell response to mouse cytomegalovirus is generated by mature subsets of varying proliferative ability

Darren Wethington, Saeed Ahmad, Marc Potempa…·Jayajit Das

This study quantifies how clonal stochasticity in NK cell responses to MCMV arises from proliferation and death dynamics of mature NK subsets.

DOI 10.7554/elife.104951

mouseflow cytometry

𝕏 PostBluesky