William C. Stewart

The paper develops a multiscale computational model to predict CD33 CAR-NK cytotoxicity against various target cells using experimental data and flow cytometry.

The paper develops a stochastic model to predict T cell clone size distributions in brain tumors and finds faster proliferation in metastases and stronger responses to shared neoantigens.

This study shows that NK cell receptor signaling and activation vary with cell cycle stages, with some proteins showing non-monotonic abundance changes.

The paper examines spatial fencing patterns of tumor cells by immune and non-immune cells in solid cancers and links these patterns to cancer progression and treatment response.

The paper develops a spatially resolved model to show how immune cell organization and dynamics influence response to immune checkpoint inhibitors in melanoma patients.