Amrutha Kizhedathu

This study shows cyclin B3-CDK1/2 drives mitotic progression and fidelity in cancer cells, with overexpression accelerating mitosis and depletion disrupting it in multiple cancer models.

This study shows that cyclin B3-CDK1 promotes mRNA de-repression in C. elegans embryos by degrading OMA proteins, linking mitosis to early gene expression.

This study identifies cyclin B3 as the key driver of rapid mitoses in early C. elegans embryos, showing it enables faster cell division compared to cyclin B1 and B2.

The paper shows Duox-generated ROS activates ATR/Chk1 to induce G2 arrest in Drosophila tracheoblasts through a non-canonical mechanism.