Cancer BiologybioRxivPreprint
Clinically relevant orthotopic pancreatic cancer models for adoptive T cell therapy
Natalie K. Horvat, Isaac Karpovsky, Maggie Phillips…·Gregory B. Lesinski
This study compares two orthotopic PDAC mouse models to evaluate their suitability for studying adoptive T cell therapy, finding that the MT-5 model better replicates the stromal features of human PDAC.
DOI 10.1101/2023.09.07.556707