Author

Hiroko Masamune

ORCID 0009-0006-4313-3649Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Anna LechneriD· 1 shared Bethany K. OkadaiD· 1 shared Fumiya K. SanoiD· 1 shared Gabriella Costa Machado da CruziD· 1 shared Hiroaki AkasakaiD· 1 shared Mark J. BurkiD· 1 shared Osamu NurekiiD· 1 shared Peter A. JordaniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Anna LechnerORCID

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1 paper

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedApr 22, 2025

Structure of a lasso peptide bound ETB receptor provides insights into the mechanism of GPCR inverse agonism

Wataru Shihoya, Hiroaki Akasaka, Peter A. Jordan…·Osamu Nureki

The paper reports cryo-EM structures of the ETB receptor bound to the lasso peptide RES-701-3, revealing its inverse agonist mechanism through hydrophobic interactions and conformational stabilization.

9 citations

humancryo-EM

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