Timothy Pan

Hypatia compares isoform complexities across cell populations using long-read single-cell transcriptomes, improving detection of isoform usage shifts and diversity.

This paper introduces LongFUSE, a tool for detecting fusion genes in single-cell long-read RNA sequencing data, showing improved accuracy over existing methods.

This study identifies AP-1 transcription factors as key regulators of TRM development across tissues using scRNA-seq and ATAC-seq, revealing a novel mechanism for TRM reactivation.

The paper introduces scNanoGPS, a toolkit for analyzing long-read single-cell transcriptomes to infer cell genotypes and phenotypes without short-read data, revealing cell-type-specific isoform and mutation patterns in tumors.