Dennis Goldfarb

This study identifies TMEM106B as an alternative receptor for SARS-CoV-2 S-E484D variant entry, independent of ACE2, in airway-derived cell models.

Pioneer and Altimeter provide fast, accurate analysis of DIA proteomics data, improving peptide coverage and speed compared to existing tools.

This paper designs a protein inhibitor for UBE2D enzymes to study their role in ubiquitination, showing it reduces Ub degradation and proteotoxic stress in HeLa cells.

The paper uses proximity proteomics to identify proteins interacting with Afadin in MDCK cells, revealing new adherens junction components and their overlap with other junctions.

This study identifies tonic activation of the cGAS-STING and IFN pathways in ACE2-positive airway cells as a factor limiting SARS-CoV-2 replication.

This paper identifies a brown adipose tissue-secreted protein fraction that improves glycemia in T1D mice independently of insulin, with nidogen-2 as a key component that inhibits glucagon secretion.

This study shows poly-lysine peptides and their modifications can reduce Plasmodium falciparum in human erythrocytes in vitro, with potential as new antimalarial drugs.