Roaa Khafaji

This study identifies Sirt-1 as a host factor required for optimal LCMV multiplication and suggests repurposing Sirt-1 inhibitors as antivirals.

This paper shows halofuginone inhibits mammarenavirus replication by targeting prolyl-tRNA synthetase, leading to translation inhibition and reduced viral budding.

This study shows that NMT inhibition reduces mammarenavirus replication by impairing Z protein budding and GP2 fusion activity.

This study shows that PKR activation can both restrict and enhance LCMV replication, revealing a complex role for PKR in mammarenavirus infection.