This study examines the behavioral and metabolic effects of PTH in mouse models of hyperparathyroidism, finding sex-specific behavioral changes and metabolic alterations.

DOI 10.1016/j.isci.2026.116650

mouseexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintJun 28, 2026

Peri-Locus Coeruleus Controls Endothelial Cell Heterogeneity in Enriched Environments via Region-Specific Norepinephrine Signaling

Y ZHAO, Botai Li, Furong Ju…·Fan Yang

This study shows that peri-LC neurons regulate bone endothelial heterogeneity and density through norepinephrine signaling in enriched environments.

DOI 10.64898/2026.06.23.733358

mouseexperimental assay

𝕏 PostBluesky

Cell BiologybioRxivPreprintDec 22, 2023

Identification of a Novel Ferroptosis Inducer with Dual Modulatory Effects on GPX4 Activity and Stability

Jun Wang, Long Liao, Bo Yang…·Cun Wang

This study identifies MI-2, a novel GPX4 inhibitor that induces ferroptosis by inhibiting GPX4 activity and promoting its degradation, showing synergistic effects with existing cancer drugs.

1 citation

experimental assaycancer & tumor microenvironment

𝕏 PostBluesky