Mohammed Ali H. Alfadhel

This study examines depth-dependent changes in cerebral oxygenation in Alzheimer's disease models, finding that tau disrupts oxygen levels and that neuronal loss is not due to local hypoxia.

This study shows neuroinflammation increases oxygen extraction in early Alzheimer's disease without significantly altering vascular oxygen supply in a mouse model.

This study shows aerobic exercise improves microvascular perfusion and oxygenation in deep brain regions of aged mice, correlating with better cognitive function.