Author

Sophie L. Granger

University of IowaORCID 0009-0007-3581-7853Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Maria SpiesiD· 2 shared Masayoshi HondaiD· 2 shared Paras GauriD· 2 shared Blaine A. Williams· 1 shared Divya S. BhatiD· 1 shared Edwin AntonyiD· 1 shared Fletcher E. BainiD· 1 shared Jenna E. Heinen· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersBiophysics

Maria SpiesORCID

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2 papers

Recent·Most cited

BiophysicsNucleic Acids ResearchPeer-reviewedSep 12, 2024

Human hnRNPA1 reorganizes telomere-bound Replication Protein A

Sophie L. Granger, Richa Sharma, Vikas Kaushik…·Maria Spies

The paper shows hnRNPA1 remodels RPA bound to telomeric ssDNA, forming a ternary complex regulated by TERRA.

5 citations

humanproteomics

𝕏 PostBluesky

BiophysicsInternational Journal of Molecular SciencesPeer-reviewedJun 17, 2023

Single-molecule analysis of the improved variants of the G-quadruplex recognition protein G4P

Paras Gaur, Fletcher E. Bain, Masayoshi Honda…·Maria Spies

The paper analyzes the binding kinetics and selectivity of G4P and its variants using single-molecule techniques, finding that increasing RSM units enhances affinity for telomeric G4s.

6 citations

humanproteomics

𝕏 PostBluesky