Kristian Serafimov

This study shows acidosis enhances fatty acid uptake in endothelial cells, leading to lipid droplet formation, ER stress, and reduced nitric oxide, contributing to endothelial dysfunction.

The paper introduces UCL-MetIsoLib, a high-resolution metabolomics library for isomer-resolved profiling, validated across multiple biological matrices and applied to colorectal cancer organoids.

This study investigates how MASH impairs endothelial function via NO-dependent mechanisms and identifies ADMA as a key liver-derived mediator.

This study identifies mitoBKCa, a BKCa splice variant in mitochondria of breast cancer cells, showing it modulates energy production and promotes proliferation, suggesting it as a potential therapeutic target.